Double Antibiotic First Aid Ointment, containing bacitracin zinc and polymyxin B sulfate, is a topical medication used to prevent and treat minor skin infections caused by bacteria. It works by stopping the growth of bacteria and killing existing bacteria on the skin. This medication may be used to treat cuts, scrapes, burns, and other minor wounds to prevent infection and promote healing. It can also be used as a preventative measure for people at risk of developing skin infections. It should only be used on the skin and not ingested or used in the eyes or mouth.